Biographical sketches of authors

Christopher Lee   University of California, Los Angeles, Department of Chemistry and Biochemistry, Los Angeles, California 90095-1570 (electronic mail: leec@mbi.ucla.edu). Dr. Lee is assistant professor and director of the UCLA bioinformatics program. He received a bachelor's degree in biochemistry and molecular biology from Harvard University in 1988, and a Ph.D. degree in structural biology from Stanford University in 1993. He has developed a variety of bioinformatics software, including CARA (protein mutant modeling), LOOK, and GeneMine (for gene function analysis and automated annotation), POA (multiple sequence alignment), and SNP-ASSESS (polymorphism detection). His recent research has focused on statistical analyses of human genome data, including identification of evidence for single nucleotide polymorphisms and alternative splicing. More information can be found at http://www.bioinformatics.ucla.edu/leelab.

Kris Irizarry   University of California, Los Angeles, Department of Chemistry and Biochemistry, Los Angeles, California 90095-1570 (electronic mail: irizarry@mbi.ucla.edu). Mr. Irizarry is a Ph.D. degree candidate in the UCLA bioinformatics program and a research assistant in Dr. Lee's group. He has worked on a wide variety of research projects including Drosophila developmental genetics, identification of single nucleotide polymorphisms (SNPs), and construction of SNP-based maps of the human genome. Before coming to UCLA, he studied biochemistry and biophysics at Rensselaer Polytechnic Institute.