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2.2- Probabilistic Analysis

As we have just seen, the deterministic approximation is useful for estimating some important characteristics of epidemics -- the conditions under which they occur, the rate at which they grow, and the expected number of infections once they have reached equilibrium. However, since it ignores the stochastic nature of an epidemic, it provides no information about other important features of the dynamics, including the size of fluctuations in the number of infected individuals and the possibility that fluctuations will result in extinction of the infection. Consider for a moment the issue of the survival of the virus in a population. The deterministic analysis concludes that there will be an epidemic if tex2html_wrap_inline1366 and there will not be one if tex2html_wrap_inline1368 . However, it is intuitively clear that, even if tex2html_wrap_inline1370 , a statistical fluctuation might wipe out the virus before it spreads to enough individuals to become firmly established. With a little more effort, we can formulate an approximate probabilistic analysis which captures these and certain other important aspects of epidemics which can not be obtained from a deterministic analysis.

As in the deterministic analysis of the previous section, we shall assume that the number of infected nodes sufficiently characterizes the state of a system, i.e., the details of which nodes are infected are relatively unimportant. Although it is very easy to construct particular graphs for which such details are important (e.g., small graphs with a large variation in the in-degree and out-degree of nodes), we assume that the properties of most members of the class of random graphs with N nodes and edge probability p will not be sensitive to them. Again, we must resort to simulation (in section 2.3) to test the validity of these assumptions. First, we shall describe the probabilistic approximation. Then, we shall use it to calculate various quantities of interest.




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